Adenosine is a neuromodulator with receptor-mediated effects. De novo synthesis of adenosine in brain is low 1; thus, adenosine is primarily derived from dephosphorylation of ATP. In physiological ...

Instantaneous wave-free ratio (iFR), a pressure-only measure of stenosis severity, is comparable to fractional flow reserve (FFR) without the use of adenosine Results of the ADVISE Trial Reported at ...