Researchers discover that some low-affinity immunomodulatory antibodies have greater anticancer activity than those with high affinity. Antibodies’ ability to bind specifically and tightly to target ...

Antibodies have a remarkable capacity to recognize specific parts of proteins called antigens, particularly those associated with disease or infection. B cells of the immune system make antibodies, ...

Researchers have developed a new AI tool that predicts tight-binding antibodies and can be used to streamline antibody discovery efforts. Antibodies’ ability to bind specifically and tightly to target ...

Antibodies play a vital role in the immune system by providing protection against foreign invaders, such as bacteria and viruses. Produced by B cells, antibodies are protein molecules that can be ...

Scientists developed an artificial intelligence tool that could accelerate the development of new high affinity antibody drugs. Scientists at University of California San Diego School of Medicine have ...

Artificial intelligence was used to aid the discovery of high-affinity antibodies, which are typically identified through directed evolution—a process that requires rounds of mutagenesis and selection ...

Assessing the pharmacokinetics (PK) of antibody-drug conjugates (ADCs) in both preclinical and clinical settings is crucial for their development. Biotransformation processes can lead to the creation ...