B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), challenging the ...
University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – ...
CAR-M therapy LIB820 may deplete disease-driving B-cells in MS and other autoimmune diseases without severe side effects, new ...
B-cell chronic lymphocytic leukemia (CLL) is a type of cancer that causes abnormal B cells, a type of white blood cell that makes antibodies. Leukemia is a broad term for cancers that affect the blood ...
B-cell prolymphocytic leukemia (B-PLL) is a rare, aggressive type of leukemia that progresses rapidly. People with B-PLL typically have a less favorable outlook. However, new targeted treatments in ...
Deep in the lungs, resident memory B cells stand guard against influenza reinfection—but whether they remain there may depend on how strongly they are signaled through their own receptors. New ...
At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody ...
About five million people worldwide have systemic lupus erythematosus (SLE), an autoimmune disease that damages organs and tissues throughout the body, including skin, joints, kidneys, heart, and ...
Researchers headed by a team at Seattle Children’s Research Institute have shown for the first time that engineered human plasma B cells can be used to treat a disease—more specifically leukemia—in a ...
Precursor B-cell acute lymphoblastic leukemia is a fast-growing leukemia that affects early B cells in bone marrow. It’s both more common and has a better outlook in children. Leukemia is a type of ...