The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

On injury, when a blood vessel is damaged, it immediately constricts to reduce blood loss. The platelets (tiny cellular fragments that are present in blood) come together to form a plug. This plug is ...

A recent study provides new insights into the mechanisms of coagulation in persons with haemophilia A, the most common form of haemophilia. The research team was able to show that saliva contains ...