Move over karyotypes—genetic disorder detection has vastly improved. Researchers are now using array CGH (aCGH), to quickly scan through an entire genome for imbalances.

High Frequency of Submicroscopic Hemizygous Deletion Is a Major Mechanism of Loss of Expression of PTEN in Uveal Melanoma Skin biopsy samples of 31 patients with a PCLBCL classified as either primary ...

Agilent Technologies Inc. and Cogenics, a division of Clinical Data, Inc. have announced that Cogenics has been recertified, for the third year, as a Certified Microarray Service Provider for Agilent ...

The "capture" can be realized through the hybridization of fragmented DNA with baits complementary to regions of interest, either on a microarray chip or free in solution. In-solution hybridization ...

Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

Researchers at Baylor College of Medicine (BCM), Houston, Texas, have, for the first time, observed a way that DNA additions or deletions associated with a wide range of diseases are introduced in ...