Understanding the link between nucleotide metabolism and chromatin assembly

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...
eLife

Separating selection from mutation in antibody language models

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
News Medical

An Overview of Nucleotide Metabolism

Nucleotides are essential components of a wide range of cellular processes; therefore, the maintenance of these levels through various metabolic pathways is crucial for adequate cellular function. The ...
Science Daily

First CRISPR single-nucleotide edited transgenic mice

It is technically challenging to replace a single nucleotide with the current gene editing tool, CRISPR-Cas9. Scientists have used a variation of the popular gene editing technique CRISPR-Cas9 to ...