The use of vectors based on the small parvovirus adeno-associated virus has gained significant momentum during the past decade. Their high efficiency of transduction of postmitotic tissues in vivo, ...

An inherent problem of genetic modification of the AAV capsid is the design of the targeting peptide. Our knowledge about cell surface receptors and their ligands is incomplete, and the toleration and ...

You have full access to this article via your institution. biological response induced by TNFRII-Fc. Overall, this is an interesting and difficult study performed in a preclinical setting for ...

1 Xuzhou Key Laboratory of Laboratory Diagnostics, School of Medical Technology, Xuzhou Medical University, Xuzhou, China 2 Xuzhou Key Laboratory of Laboratory Diagnostics, School of Anesthesiology, ...

The number of Americans suffering from some form of heart disease is approaching 62 million, according to the American Heart Association. And at least 12.6 million of those individuals suffer from ...

Gene therapy achieved its first major breakthroughs in the early 1990s with the treatment of a rare disease called severe combined immunodeficiency. However, the field was dealt a serious setback in ...