Anthrax toxin protective antigen (PrAg) forms a heptamer in which the binding site for lethal factor (LF) spans two adjacent monomers. This suggested that high cell-type specificity in tumor targeting ...
CAPN3/p94/calpain-3, a calpain protease family member, has uniquely rapid and exhaustive autolytic activity. Here, we demonstrate that active protease core domain of CAPN3 is reconstituted by de novo ...
Department of Biological Information, Graduate School of Bioscience and Biotechnology, 4259, Nagatsuta, Midori-ku, Yokohama, 226-8501, Japan, and Department of Applied Chemistry, Faculty of ...
Figure 1: The PLC-γ1 PH-c domain binds directly to amino acids 40–46 in TRPC3. Figure 2: TRPC3 possesses an invisible PH-n domain at the site of PLC-γ1 PH-c binding. Our gestalt algorithm for ...
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