Potent, selective ABCC6-targeting positive functional modulator (PFM) improved multiple markers of renal function in animal models of chronic kidney disease (CKD) PFM improved inorganic pyrophosphate ...
Through advances in both basic and clinical scientific research, Pavlovian fear conditioning and extinction have become an exemplary translational model for understanding and treating anxiety ...
Unravelling how neural circuits generate complex behaviours remains one of the most compelling challenges in neuroscience. This endeavor requires tools that ...
The translational readiness of this program makes it a compelling de-risked asset with the potential to address CKD and multiple cardiovascular indications.” Title: A Positive Functional Modulator of ...
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