Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...

Hsp90 plays a central role in cell homeostasis by assisting folding and maturation of a large variety of clients. It is a homo-dimer, which functions via hydrolysis of ATP-coupled to conformational ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 12 (March 25, 2014), pp. 4455-4460 (6 pages) The cyanobacterial circadian oscillator can be reconstituted ...