Adherens junctions, the sites of cadherin-dependent cell–cell adhesion, are also important for dynamic tension sensing, force transduction and signalling. Different myosin motors contribute to ...

Calcium's Role in Unveiling the Active Sites: In a resting muscle, the myosin-binding sites on actin are blocked by a protein complex called tropomyosin. Tropomyosin is a long, rod-shaped molecule ...

Skeletal and heart muscles contract and relax upon sliding of parallel filaments of the proteins myosin and actin. Nebulin, another long slender protein, which is present only in skeletal muscle, ...

Over the last several years the identification and functional characterization of the motor proteins actin and myosin in the nucleus has initiated a change in the view of nuclear processes. It is now ...

Point mutations in vascular smooth muscle α-actin (SM α-actin), encoded by the gene ACTA2, are the most prevalent cause of familial thoracic aortic aneurysms and dissections (TAAD). Here, we provide ...

This is a preview. Log in through your library . Abstract Acanthamoeba myosin-I bound to substrates of nitrocellulose or planar lipid membranes on glass moved actin filaments at an average velocity of ...

The actin and myosin complex (actomyosin) generates contraction force of a muscle utilizing the adenosine triphosphate (ATP) hydrolysis reaction. Many attempts have thus been made to explain the ...

A research team led by Biological Sciences Asst. Prof. Nicolai Konow will work across disciplines to develop a deeper understanding of how muscles function. “Everything has to be broken down to its ...

The standard textbook model of muscle contraction includes only two main players, the filaments actin and myosin, which slide past each other, causing the sarcomere—the basic unit of muscle tissue—to ...