We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Studies assessing bronchoscopic lung volume reduction ...

Alpha-1 antitrypsin (AAT) deficiency is a clinically under-recognized genetic disorder that causes the defective production of alpha-1 antitrypsin protein. AAT protein protects the body from the ...

Alpha-1 antitrypsin deficiency (AATD) is a hereditary condition characterised by the misfolding of the alpha-1 antitrypsin (AAT) protein, resulting in its hepatic accumulation and compromised protease ...

: Alpha-1-antitrypsin (AT) deficiency is the most common genetic cause of liver disease in children. In addition to chronic liver inflammation and injury, it has a predilection to cause hepatocellular ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Augmentation therapy increased survival in patients with ...

Background: Two separate genome-wide association studies demonstrated that polymorphisms in SERPINA1, encoding serine protease inhibitor alpha-1 antitrypsin (A1AT), are associated with increased risk ...

Alpha-1-antitrypsin is a so-called protease inhibitor, a type of enzyme inhibitor. It is produced in the liver but exerts its effects in the lungs, where it regulates immune cell activity. This ...

Exacerbations are common in individuals with alpha-1-antitrypsin deficiency (AATD) related lung disease. This study intended to identify independent predictive factors for exacerbations in AATD using ...

The following is a summary of the study, “Longitudinal evaluation of individuals with severe alpha-1 antitrypsin deficiency (Pi*ZZ genotype),” published online in Gastroenterology in October 2024 by ...

MIAMI, Jan. 24 /PRNewswire/ -- The Alpha-1 Foundation, in conjunction with the American Association for the Study of Liver Diseases (AASLD) has organized a Basic Research Single Topic Conference on ...

Alpha-1-antitrypsin is a protein produced by the liver. The protein gets secreted to the blood stream, where it circulates the body to protect the lungs. However, some people are born with genetic ...