Cell migration through 3D extracellular matrices (ECMs) is crucial to the normal development of tissues and organs and in disease processes, yet adequate analytical tools to characterize 3D migration ...

Three-dimensional (3D) cell culture methods have been widely used on a range of cell types, including stem cells to modulate precisely the cellular biophysical and biochemical microenvironment and ...

Cells evolve within intricate, fiber-rich microenvironments that present significant challenges for studying their behavior and mechanics. To address this, we employed advanced three-dimensional (3D) ...

A recent study suggested that the total number of unique species that call Earth home may be as mind-bogglingly high as 1 trillion. Granted, the vast majority of those are microscopic organisms, but ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

Yu Song (left) and Ting Zhang (right) from Tsinghua University are using 3D cell printing to engineer brain-like tissue constructs. (Courtesy: Biomanufacturing and Rapid Forming Technology Key ...

Advanced 3D spheroid models are being widely acknowledged as a vital tool for better evaluation of cancer immunotherapy agents in-vitro. This article describes the potential to kinetically visualize ...

In the new study, the team used the model to demonstrate that as Alzheimer's pathology accumulates in the brain, specific types of immune cells called CT8+ T Cells surge into the brain and amplify the ...