Ataxia is the defect in normal movements like walking, speaking, eating swallowing etc. It is caused most commonly by damage to the brain stem or cerebellum that regulates movements. There are over 50 ...

Autosomal dominant cerebellar ataxia (ADCA) is a genetically heterogeneous group of neurodegenerative disorders. To shed further light on the clinical and genetic spectrum of ADCA in Japan, we ...

Ataxia is a form of movement disorder. There is loss of balance and physical co-ordination leading to difficulty in walking normally. The Cerebellum of the brain is normally responsible for ...

Spinocerebellar ataxia (SCA) is a progressive, degenerative, genetic disease that has multiple types. It is characterized by slowly progressive incoordination of gait, often associated with poor ...

Episodic ataxia type 1 (EA1) is a rare autosomal potassium channelopathy, due to mutations in KCNA1. Patients have childhood onset of intermittent attacks of ataxia, dizziness or imbalance. In order ...

Autosomal recessive cerebellar ataxias (ARCAs) are rare and early-disabling neurodegenerative-movement disorders caused by dysfunction in the cerebellum. The most common form is Friedreich ataxia. A ...

Spinocerebellar ataxia type 10 (SCA10) is a rare autosomal dominant cerebellar ataxia caused by nucleotide ATTCT expansion in ATXN10 gene. SCA10 has been reported in patients of cerebellar ataxia from ...

eDepartment of Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan fDepartment of Neurology and Neurological Science, Graduate School of Medical and Dental ...