In July 2003, the National Institute of Child Health and Human Development (NICHD) organized a consensus conference, where a group of experts were invited to review and discuss the current state of ...

Serum bilirubin measurements are commonly obtained for the evaluation of ill patients and to screen for liver disease in routine physical exams. An enormous research effort has identified the multiple ...

Genetic-based susceptibility to bilirubin neurotoxicity and chronic bilirubin encephalopathy (kernicterus) is still poorly understood. Neonatal jaundice affects 60–80% of newborns, and considerable ...

Low levels of bilirubin lead to more chances of brain damage, suggesting that bilirubin protects brain cells from superoxide reactions. In studies in mice, Johns Hopkins Medicine researchers report ...

Bilirubin is a component of the heme catabolic pathway that is essential for liver function and has been shown to reduce hepatic fat accumulation. High plasma bilirubin levels are reflective of liver ...

In studies in mice, Johns Hopkins Medicine researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected ...

Department of Physiology and Biophysics, Center for Excellence in Cardiovascular – Renal Research, University of Mississippi Medical Center, Jackson, MS, USA Bilirubin is generated from the breakdown ...

While biliverdin reductase A (BVRA) is classically known as the biosynthetic enzyme for the metabolite and antioxidant bilirubin, we report here that it also exerts nonenzymatic antioxidant activity ...

In studies in mice, researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting ...

Gilbert syndrome (GS) is characterised by a lifelong genetically determined elevation of plasma unconjugated bilirubin levels.1 This typically entails decreased hepatic expression of the enzyme that ...