The thymocyte-specific special AT-rich sequence binding 1 (SATB1) protein binds to base unpairing regions (BUR) within matrix attachment regions and assembles a SATB1 network structure that can ...
In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...
In a recent study published in the journal Nature, researchers identify the mechanisms through which double-stranded break (DSB)-induced compartment formation orchestrates the deoxyribonucleic acid ...
In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...
Nucleosomes (blue sphares) in active chromatin regions form condensed domains with local nucleosome contacts and cohesin (rings), where nucleosomes fluctuate. Each interphase chromosome (highlighted ...
Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted ...
The nuclei of most human cells contains the entire genome, which would have a length of about six feet if it was fully extended. So this DNA has to be carefully compacted in cells, while still ...
The researchers also point out that chromatin condensation and organization may play an important role in cell differentiation, or specialization, as the chromatin domains of undifferentiated ...
The human genome and its DNA are often presented in a single dimension in biology textbooks and educational materials. While introducing DNA as a linear sequence that produces genes can help students ...
It is still not fully understood how, despite having the same set of genes, cells turn into neurons, bones, skin, heart, or roughly 200 other kinds of cells, and then exhibit stable cellular behavior ...
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