Antisense oligonucleotides (ASOs) are small, single-stranded molecules that can suppress the expression of targeted genes and thereby achieve therapeutic effects. However, many ASO-based drug ...

Researchers in China have developed a new method that allows them to insert long stretches of DNA into a genome. The process, named GRAND editing, is one of a handful of new systems aimed at using two ...

American geneticist who shared a Nobel Prize for discovering the double helix structure of DNA. Born on April 6, 1928 in Chicago, IL, USA, he died aged 97 years in East Northport on Long Island, NY, ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...

DNA replication, the fundamental process of copying a DNA molecule, is described as semiconservative due to its unique ...

The most recognizable feature of dsDNA is its double helix structure, often likened to a twisted ladder. This elegant structure, first proposed by James Watson and Francis Crick in 1953, is formed by ...

The term ‘DNA’ immediately calls to mind the double-stranded helix that contains all our genetic information. But the individual units of its two strands are pairs of molecules bonded with each other ...

Researchers from Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, USA, report a modification wherein replacing the RNA strand of a heteroduplex oligonucleotide with DNA may ...