The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

DNA methylation plays a critical role in developmental and physiological processes, where aberrant methylation can lead to a variety of disease states including cancer. Cell-free DNA (cfDNA) samples ...

In this Teach Me in 10 episode, Technology Networks welcomes Zahid Ahmed, Senior Support Scientist at Roche Sequencing and Life Science. Zahid offers an in-depth exploration of digital PCR (dPCR) ...

DNA has tremendous potential as a data storage medium, but the process of synthesizing DNA from scratch is time-consuming. It has to be done one nucleotide at a time in a specific sequence. New ...

In this ‘Peek behind the paper’, Elena Martens-Uzunova (left), Assistant Professor in the Department of Urology at the Erasmus University Medical Center (Rotterdam, The Netherlands), discusses her ...

Promising new inroads into critical DNA testing has been forecast by experts who have applied machine learning to DNA profiling. From medical diagnostics to forensic tests and national security, PCR ...

An AI model has been trained to recognize DNA methylation signatures of 13 different types of cancer. Researchers at the University of Cambridge and Imperial College London (both UK) present an AI ...

An international team led by UPV/EHU and Biobizkaia reveals the relationship between placental DNA methylation and certain neuropsychiatric disorders. An international team, led by the Immunogenetics ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.