A research team led by scientists at the Icahn School of Medicine at Mount Sinai (ISMMS) has solved the three-dimensional structure of a key protein that helps damaged cellular DNA repair itself.

A new study published in Nature Structural & Molecular Biology reveals how the fundamental enzyme called DNA polymerase delta operates during DNA replication, making a copy of the genetic code that ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

DNA is the molecule that holds the instructions for all living things. DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Check your ...

In all living organisms, proliferating cells go through the fundamental process of DNA replication. Through this process, they faithfully duplicate their DNA and divide into two daughter cells. In ...

Faithful duplication of the genome requires structure-specific endonucleases such as the RuvABC complex in Escherichia coli. These enzymes help to resolve problems at replication forks that have been ...

A map of DNA with the double helix colored blue, the landmarks in green, and the start points for copying the molecule in red. David Gilbert/Kyle Klein, CC BY-ND David Gilbert / Kyle Klein, CC BY-ND ...