Preclinical development of human cells for potential therapeutic application in neurodegenerative diseases requires that their long-term survival, stability and functional efficacy be studied in ...

Drug hypersensitivity reaction is an immune-mediated reaction to a drug. Hypersensitivity reactions may vary in severity from mild to life-threatening. Reactions prompt the discontinuation of the ...

Our brain's reward system processes and reinforces pleasurable experiences, motivating us to seek out and engage in rewarding activities ranging from eating to social interactions to recreational drug ...

One evidence-based technique in psychotherapy for overcoming anxiety is desensitization. By repeatedly facing threatening situations under calm, controlled emotional conditions, we learn to respond in ...

Systematic desensitization is an evidence-based therapy approach that combines relaxation techniques with gradual exposure to help you slowly overcome a phobia. During systematic desensitization, also ...

β-Arrestins bind to activated G protein-coupled receptor kinase-phosphorylated receptors, which leads to their desensitization with respect to G proteins, internalization via clathrin-coated pits, and ...

For most phobias, systematic desensitization, developed by Joseph Wolpe, can be used to gradually expose the amygdala to a phobic situation. By gradual exposure, the amygdala becomes accoustomed to ...

Behavior patterns of chemotactic mutants of Salmonella typhimurium were compared to those of the wild type by using the quantitative tumble frequency assay. Some cheU mutants were completely inverted ...

Drug desensitization is the process by which a patient is densensitized to a drug that they allergic to in the past. This induces a temporary state of tolerance, during which the drug can be ...