A study in Scientific Reports evaluated a photoacoustic polydopamine-indocyanine green (PDA-ICG) nanoprobe for detecting senescent cells. Senescent cells play a role in tumor progression and ...

TOKYO — Doctors may eventually be able to tell whether your cells are aging prematurely without needles, blood tests, or expensive lab work. Japanese researchers have developed an experimental ...

Kidney fibrosis, a common endpoint of chronic kidney disease (CKD), is strongly linked to aging, with cellular senescence emerging as a key driver in its pathogenesis. This overview synthesizes ...

Aging is a complex biological process characterized by the progressive decline of physiological integrity, leading to impaired function and increased vulnerability to disease. It is the strongest risk ...

The quest for rejuvenation treatments often targets senescent cells, despite them having a positive physiological role in health in many recent cases, a leading researcher has warned. In a paper ...

A research team led by Professor Takuya Yamamoto (Department of Life Science Frontiers) and Professor Yasuhiro Yamada at the University of Tokyo has developed a novel in vivo system that reveals how ...

This illustration shows the major cell types affected by cellular senescence in various skeletal diseases. As the body ages, senescent cells accumulate in different tissues—including bone, cartilage, ...

As time marches on, aging is inevitable. Naturally, a person can accumulate wrinkles, laugh lines, stress, and cellular damage. Of these, damaged cells can take multiple paths: they can undergo ...

Osaka University researchers discovered AP2A1 protein's significant role in cellular aging; lowering its levels reversed aging characteristics. They also found drug IU1, which inhibits USP14, enhances ...