Nature

A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28

Figure 1: Requirement of PKC-θ V3 for localization to the immunological synapse, cSMAC and signaling. Figure 2: The PKC-θ V3 domain is required and sufficient for CD28 interaction. Figure 3: A proline ...
Nature

Replication competent helper functions for recombinant AAV vector generation

Adeno-associated virus (AAV) is a promising gene transfer vector tested in both animal studies and human clinical trials. However, current production methods are generally inefficient and require ...