Transcription refers to the creation of a complimentary strand of RNA copied from a DNA sequence. This results in the formation of messenger RNA (mRNA), which is used to synthesize a protein via ...

Transcription factors are genes that, once expressed, can influence the activity of other genes, sometimes many other genes. There are hundreds of transcription factors in human cells that we know of, ...

Researchers have been on an ongoing quest to target transcription factors (TFs), a notoriously hard-to-block class of proteins that, when mutated or dysregulated, can disrupt cell function and drive ...

Journal of Applied Probability, Vol. 47, No. 4 (DECEMBER 2010), pp. 1023-1033 (11 pages) In this paper we study the Wiener—Hopf factorization for a class of Lévy processes with double-sided jumps, ...

Treatments targeted to enhance brain neurotrophic factor signaling could improve memory functions in Alzheimer's disease even though they don't alter brain amyloid burden, according to recent research ...

For years, scientists have known that the anti-aging hormone klotho, infusions of young blood, and exercise each improve brain function in older mice. But they didn’t know why. Now, two UC San ...