Plasma fibronectin has been proposed to play a role in wound healing. Studies with conditional knockout mice, however, indicate that fibronectin has more to do with protecting cells from ischemic ...
The matrix fibronectin protein is a multifunctional adhesive molecule that promotes migration and invasiveness of many tumors including melanomas. Increased fibronectin synthesis has been associated ...
Background: Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) accounts for up to 15% of acute Myocardial Infarction (MI) cases and presents significant diagnostic and therapeutic ...
Post-traumatic osteoarthritis (PTOA), a subtype of osteoarthritis initiated by joint trauma, is driven by unresolved early inflammation that ultimately leads to cartilage degeneration. Although animal ...
On the adhesion–velocity relation and length adaptation of motile cells on stepped fibronectin lanes
Cells exert forces on their environment by contracting actin networks, friction of intracellular F-actin flow, and polymerization when they move, e.g., during tumor metastasis or development. In this ...
Our recent studies found a reduction in specific GSLs (Gg4 and/or GM2) in the EMT process induced by transforming growth factor β (TGF-β) in mouse and human epithelial cells (16). Further studies with ...
Conclusions— Our findings reveal that EDA + FN has prothrombotic activity, and its presence in plasma may worsen pathological conditions in which this form is elevated. Figure 1. Fibronectin levels ...
The fibronectin‐leucine‐rich transmembrane (FLRT) family of leucine‐rich repeat (LRR) proteins is implicated in fibroblast growth factor (FGF) signalling, early embryonic development and neurite ...
The extracellular matrix (ECM) protein fibronectin is involved in several stages of embryogenesis. Fibronectin exerts its effect through interaction with cellular integrin and nonintegrin receptors.
Abstract—Vascular calcification is a frequent component of atherosclerosis, yet the pathological mechanisms that regulate its formation are poorly understood. Calcification of the vessel wall may ...
This is a preview. Log in through your library . Abstract The fibronexus (FNX), a very close transmembrane association of individual extracellular fibronectin fibers and actin microfilaments, was ...
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