Glycosylation is one of the most abundant of all protein post-translational modifications (PTMs). It results from the addition of sugar residues to protein sidechains to form a glycoprotein. Mammalian ...

A comprehensive study mapped the dynamic glycosylation landscape of rat serum proteins, uncovering sex- and time-dependent variations with clear cell-type specificity. Researchers found distinct ...

A new study shows that gut bacteria can influence the molecular pattern of glycosylation—the presence of sugar groups on proteins—in the brain. Credit: Daniela Velasco Lozano/EMBL Our guts are home to ...

Using new methodology, University of Kentucky researchers have mapped the variations in sugar chains attached to brain proteins from deceased healthy individuals or individuals with Alzheimer's ...

A new study shows that gut bacteria can influence the molecular pattern of glycosylation – the presence of sugar groups on proteins – in the brain. Our guts are home to trillions of bacteria, and ...

Sites of O-glycosylation on the spike protein were near N-glycosites, suggesting O-glycans complement N-glycans' effect in immune shielding. The severe acute respiratory syndrome coronavirus 2 ...

The microbes in the human gastrointestinal tract can have a significant influence on human health and disease, and this gut microbiome has been associated with a wide array of characteristics and ...

Post-translational modifications (PTM)—chemical transformations that occur after a protein’s translation from RNA—include numerous changes, some well known and others quite obscure. Modifications ...

Glycoproteins containing heavily O-glycosylated, mucin-like, domains play important and diverse biological roles for example, protecting cell surfaces, modulating cell-cell interactions, targeting ...

With a worldwide footprint, CD BioGlyco offers pioneering services in glycobiology analysis, ranging from glycoprotein enrichment and glycosylation-site mapping to site-specific quantification and ...