A pair of papers published this week in the two leading scientific journals mark the completion of the Human Genome Project and the start of a new project to find all of the functional elements in ...
Our ancient past isn't always buried history. When it comes to our DNA, nearly 9% of the human genome is made up of leftover ...
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DNA sequence once overlooked as ‘junk’ found to drive human chromosome fusions
Leonardo Gomes de Lima, Ph.D., a postdoctoral associate in the Gerton Lab, led the research. The findings show how these chromosome fusions form, why they remain stable, and how repetitive DNA, once ...
REPAIRome specifically addresses the repair of one of the most serious types of DNA damage, DNA double-strand breaks (DSBs).
Researchers are now exploring how different types of repetitive DNA create genome instability and structurally variant chromosomes.
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Bridge recombinases, optimized for human cells, enable massive programmable DNA rearrangements
For decades, gene-editing science has been limited to making small, precise edits to human DNA, akin to correcting typos in ...
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First Human Embryos Created Using Skin Cell DNA and Sperm
It is no longer science fiction: human embryos have now been made from DNA in skin cells that were fertilised with sperm, a move that redrafts the biological limits of reproduction. At an Oregon ...
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How long does DNA last?
The world's oldest DNA comes from a 2.4 million-year-old ecosystem in Greenland. Will scientists eventually sequence even older DNA?
Scientists have decoded the world’s oldest human DNA sequence, beating the previous record by almost 300,000 years, and at the same time confusing what we know of our early relatives. Published in ...
DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...
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