Figure 1: Molecular recognition processes for induced-fit and conformational selection mechanisms. Figure 4: Kinetic analysis of conformational dynamics for MBPs in the presence of a ligand. The ...
Allostery, the coupling between ligand binding and protein conformational change, is the heart of biological network and it has often been explained by two representative models, the induced-fit and ...
Two main models explain how an enzyme reaches the lock-and-key state: the induced-fit and the conformational selection or population-shift model. The induced-fit model features the formation of an ...