This valuable study addresses a critical and timely question regarding the role of a subpopulation of cortical interneurons (Chrna2-expressing Martinotti cells) in motor learning and cortical dynamics ...

Disruption of inhibitory interneurons is common in the epileptic brain and is hypothesized to play a pivotal role in epileptogenesis. Abrupt disruption and loss of interneurons is well-characterized ...

Researchers have developed a technique for selectively targeting and controlling the interneurons of the cerebellar molecular layer relying on a genetically engineered mouse model that exploits a ...

1 Department of Biology, University of Oklahoma, Norman, OK, United States 2 Cellular and Behavioral Neurobiology Graduate Program, University of Oklahoma, Norman, OK, United States The central ...

The knee-jerk reflex, that sudden and involuntary extension of your lower leg when the area below your kneecap is tapped, ...

One of the most important functions of interneurons in the knee-jerk reflex is to mediate reciprocal inhibition. This process ensures that the contraction of the quadriceps muscle is accompanied by ...

Neuromodulation of neural networks, whereby a selected circuit is regulated by a particular modulator, plays a critical role in learning and memory. Among neuromodulators, acetylcholine (ACh) plays a ...

There have been many attempts to understand the role of these inhibitory interneurons in cerebellar function. But as Matt Rowan, Ph.D., a Research Fellow who worked on the study mentioned, most ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, No. 10 (May 15, 1989), pp. 3911-3914 (4 pages) We used a passive, steady-state cable model to simulate current ...

San Francisco, CA--February 8, 2018--Even if you haven't ridden your bike in years, you probably remember how to do so without giving it much thought. If you're a skilled piano player, odds are you ...