Nearly 25 years after scientists completed a draft human genome sequence, many of its 3.1 billion letters remain a puzzle. The 98% of the genome that is not made of protein-coding genes — but which ...

For decades, scientists have been puzzled by large portions of the human genome labeled as “junk” DNA, sequences that seemingly serve no purpose. Yet, recent studies suggest these cryptic sequences ...

Next-generation sequencing (NGS) technologies, used to rapidly read genetic information, have consistently opened new frontiers in biology. The first NGS device – 454 Life Sciences’ Genomic Sequencer ...

We generated genome assemblies — models of genomes that are created by pasting together short lengths of sequenced DNA — for 187 primate species 3. We then aligned the whole human genome to assemblies ...

Swiss start-up Haya Therapeutics has formed a partnership with Eli Lilly – worth up to $1 billion – to look for new therapies for obesity in non-coding DNA. The biotech focuses on trawling the 98% of ...

A team of scientists from Centre for Systems and Synthetic Biology (CSSB) headed by Dr Pawan K Dhar has commenced doing research on making proteins from non-coding DNA. The objective of this research ...

Variations in non-coding sections of the genome might be important contributors to type 2 diabetes risk, according to a new study. DNA sequences that don't encode proteins were once dismissed as "junk ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Researchers from the Arc Institute have discovered a new form of gene editing that can recombine and rearrange DNA without requiring CRISPR. Published in Nature, the first DNA bridge recombinase ...