Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

Researchers have identified how a single mutation in the GPX4 enzyme causes neurons to undergo ferroptosis, leading to severe early-onset dementia.

In the natural selection theory, not a large number of mutant individuals appear at once, the mutation that "happens to the surrounding environment" happened by chance will spread over time throughout ...

Scientists have revealed parts of the genome that are especially vulnerable to mutations that occur very early on in ...

Every organism is born with a few mutations in their genome that differ genetically from both of their parents. Such changes in an individual’s genetic code create the diversity that allows nature to ...

Carlsberg has patented a method using digital PCR to identify specific nucleotide mutations in mutated genes. The process involves mutagenizing a pool of organisms, dividing them into sub-pools, and ...

Hear the latest science news, with Shamini Bundell and Benjamin Thompson. Your browser does not support the audio element. A long-standing doctrine in evolution is ...

June 5, 2014 – So-called silent DNA mutations earned their title because, according to the fundamental rules of biology, they should be inconsequential. Reported on June 5 in PLOS Genetics online, ...

A collection of over 40,000 trees in rural Utah is the world’s largest single organism, having all descended from a single seedling. But that’s not all: According to a team of researchers, the ...