Figure 1: Myosin (Myo) IIA and myosin IIB localize to apical epithelial junctions. Figure 2: Differential regulation of myosin IIA and myosin IIB localization at apical junctions. Figure 4: Homophilic ...
Hypertrophic cardiomyopathies (HCMs) are the leading cause of acute cardiac failure in young individuals. Over 300 mutations throughout β-cardiac myosin, including in the motor domain, are associated ...
Divisions of Chemistry and Biological Sciences, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan, and Celestar Lexico-Sciences, Inc., Chiba 261-8501, Japan Article Views are ...
The myosin superfamily is a group of molecular motors. Autoimmune diseases are characterized by dysregulation or deficiency of the immune tolerance mechanism, resulting in an immune response to the ...
Oxidative stress-induced neuronal apoptosis has been implicated in many central nervous system (CNS) diseases, including Alzheimer’s diseases, stroke and schizophrenia (Hayashi-Takagi et al., 2014; ...
Arecchi et al. demonstrate that polarized second-harmonic generation microscopy can be used to probe the ON/OFF states of myosin in both permeabilized and intact muscle, making this key measurement ...
From a global regulatory perspective, Cytokinetics is expanding its footprint rapidly. The drug received approval in China on ...
In a decades-long effort, researchers have discovered how to tweak the molecular pathways that turn heart muscle motors up or ...
Cytokinetics, Incorporated (Nasdaq: CYTK) today announced that the U.S. Food and Drug Administration (FDA) has approved MYQORZO™ (aficamten), 5 mg, 10 mg, 15 mg, 20 mg tablets for the treatment of ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback