In search of a possible cure for Alzheimer’s disease (AD), scientists have found out the molecular structure of a type of protein called beta amyloid that accumulates within brain cells, eventually ...

Understanding the process of fibril formation and, more specifically, the toxic beta amyloid (Aβ) protein fragments, is fundamental to advancing treatments for Alzheimer’s disease. New research ...

Multiple studies in humans and mouse models indicate that sleep disruptions raise the risk of Alzheimer’s disease (AD) by increasing the accumulation of disease-relevant proteins such as amyloid-beta ...

Amyloid-beta (A-beta) aggregates are tangles of proteins most notably associated with neurodegenerative diseases like Alzheimer's. Despite its constant stint in the limelight, however, researchers ...

Researchers have used precision-engineered nanoparticles to clear toxic proteins from the brains of mice with ...

Researchers have developed a microscopy technique to visualize amyloid beta’s underlying structure, which could yield new insights into Alzheimer’s disease. As the prevalence of Alzheimer’s rises, ...

Though there is so much to learn about the way Alzheimer's develops in the human brain, amyloid beta proteins have long been implicated in its advance. A new study has uncovered a previously unknown ...

Current interest in the toxic mechanisms of oligomeric amyloid-β proteins notwithstanding, the larger fibrils this protein forms also are neurotoxic in their own right. Recent structural studies on ...

“This is mind-blowing for a structural biologist,” said Landau. “To zoom in on something that looks exactly like an amyloid, and find α-helices instead of β-strands—it’s a total paradigm shift.” PSMα3 ...

A new blood test from Quest Diagnostics has Alzheimer's experts concerned. The Quest AD-Detect test, which consumers can now purchase from home without visiting a doctor first, measures amyloid-beta ...

Andrea Sturchio is a cofounder of REGAIN Therapeutics, owner of a provisional patent on compositions and methods for treatment and/or prophylaxis of proteinopathies, that covers synthetic soluble ...

A team has discovered that, in an animal model of Alzheimer's disease, restoring normal sleep by returning to normal the activity of the thalamic reticular nucleus (TRN), a brain region involved in ...