This milestone in cell biology -- akin to discovering 'design principles' of the cell -- unlocks the potential to find new treatments for diseases where cells malfunction. Working with hundreds of ...
Organoids—self-organizing, self-reproducing structures that serve as 3D in vitro models—date back to 2009. Back then, researchers at the Hubrecht Institute led by Hans Clevers, PhD, introduced a ...
Research and drug discovery are undergoing a transformation, driven by the rise of 3D cell culture models that better replicate human biology. Unlike traditional 2D cultures and animal models, which ...
One hallmark of many biological processes is cellular phenotypic heterogeneity. Now, a new deep learning method—AINU (artificial intelligence [AI] of the nucleus)—can identify specific nuclear ...
By implementing an automated 3D cell segmentation process, researchers mapped neurons and muscle fibers at the single-cell ...
Scientists have created one of the most detailed 3D images of the synapse, the important juncture where neurons communicate with each other through an exchange of chemical signals. These nanometer ...
Aim: This study examines the absolute quantification of particle uptake into cells. Methods: We developed a novel method to analyze stacks of confocal fluorescence images of single cells interacting ...
Researchers have developed a new groundbreaking technology that can convert some cancer cells into a state that resembles normal cells without killing them. This approach not only represents a new way ...
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