DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes. Among them, DNA–histone ...
DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.
News-Medical.Net on MSN
New research reveals the impact of DNA-histone cross-links on genome stability
DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.
Tokyo, April 14 - A research group led by Hitoshi Kurumizaka, a professor of structural biology at Waseda University, unveiled the crystal structure of an overlapping dinucleosome, a newly discovered ...
In a review published in Current Opinion in Structural Biology on May 12, researchers from the Institute of Biophysics of the Chinese Academy Sciences have reviewed the intricate molecular ...
AZoLifeSciences on MSN
DNA Rigidity Inside the Nucleosome Regulates INO80 Positioning
Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the ...
Accurate chromosome segregation requires the proper assembly of kinetochore proteins. A key step in this process is the recognition of the histone H3 variant CENP-A in the centromeric nucleosome by ...
This week in Science, Michael K. Rosen and 10 other members of a large collaboration at the Marine Biological Laboratory, the ...
It takes a lot of packaging to squeeze DNA into the nucleus of a cell. The DNA in our chromosomes is packaged into nucleosomes, which consist of about 150 DNA base pairs wrapped around eight-protein ...
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