A series of structures of the eukaryotic protein-synthesis machinery are imaged at high resolution in defined states of the elongation phase of protein synthesis. Analysis suggests that there are ...

A group of scientists has succeeded in the development of modified messenger RNAs (mRNAs) that contain sulfur atoms in the place of oxygen atoms of phosphate moieties of natural mRNAs. They discovered ...

A protein engineering method using simple, cost-effective experiments and machine learning models can predict which proteins will be effective for a given purpose, according to a new study. A protein ...

Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired. In particular, mRNA therapeutics hold the potential for ...

Cryo-EM structure of the Giardia ribosome reveals a highly compact, GC-rich rRNA with eukaryotic r-proteins. (A) Structure of the Giardia ribosome with all the r-proteins colored (SSU, shades of blue ...

Scientists from Uppsala University have used cryo-electron microscopy to reveal details of the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhoeal disease. The ...

Every living cell relies on proteins in order to function and the process of protein synthesis – translation – is critical for survival. Bacteria are no exception, with molecular machines involved in ...

When a bone grows, our bodies’ proteins help provide the structure. When a muscle tears, proteins help rebuild it. When we fight an infection, transport oxygen in our blood or send messages to a cell, ...