Researchers at Northeastern University in Boston have created a hybrid model to better understand how RNA’s structure and functional dynamics control biological systems. This modeling strategy ...
RNA plays a vital role in how our genes are expressed and how diseases develop. Yet, because RNA molecules constantly change ...
In 1965, Cornell biochemist Robert Holley deciphered the 77 nucleotide sequence of transfer RNA. Three years later, Holley was awarded the Nobel Prize for this work, but already the race to determine ...
Ribonucleic acid (RNA) is one of life's most versatile molecules, with roles going far beyond being a messenger of genetic code, as it is fundamentally involved in gene regulation, processing, and ...
New molecular dynamics research into how RNA folds into hairpin-shaped structures called tetraloops could provide important insights into new treatments for retroviral diseases. "Ribonucleic acid, ...
"Dune"-inspired Arrakis Therapeutics has tested its spice—an RNA-targeting small molecule—in a mouse model of myotonic dystrophy type 1 (DM1), with the drug reversing the prolonged muscle contraction ...
Neurodegenerative diseases, such as Alzheimer's disease and dementia, are medical conditions that entail the progressive loss ...
As the area of small molecules interacting with RNA advances, general routes to provide bioactive compounds are needed as ligands can bind RNA avidly to sites that will not affect function.
Researchers at the University of Toronto's Temerty Faculty of Medicine have found widespread genetic and protein changes in ...
A new international study led by Tel Aviv University researchers may pave the way for an effective treatment for amyotrophic ...