Objective To assess the feasibility of conducting a cluster randomised controlled trial comparing the effects of Advanced ...

Objective To provide a consistently updated overview of the comparative effectiveness of treatments for Achilles tendinopathy. Design Living systematic review and network meta-analysis. Data sources ...

The move towards a higher threshold for showing efficacy for new CAR-Ts comes after the FDA loosened the requirements for ...

Pragmatic Randomised Controlled Trial (RCTs) are the ‘gold standard’ test for evaluating whether a new intervention is better than an existing one and are routinely used in both real-world healthcare ...

Objective To identify the optimal dose and type of physical activity to improve functional capacity and reduce adverse events in acutely hospitalised older adults. Design Systematic review and ...

Objective Systemic corticosteroids for 5–7 days are standard care for asthma exacerbations, but the optimal duration and ...

A cluster randomised trial (CRT) is a randomised controlled trial in which pre-existing groups, called clusters, of individuals are randomly allocated to treatment arms. For example, clusters may be ...

The video below shows how a randomised trial works. It is about 2 minutes long. Randomised trials have at least 2 different treatment groups. The people taking part are put into one of the groups at ...

Randomised controlled trials are a proven tool for understanding the causal effects of policies. Esin Serin asks whether they can play an increased role in informing the development of effective green ...