IN a recent note 1, I discussed those reactions of organic halides in solution which involve substitution by a nucleophilic reagent at a saturated carbon atom. In reply to the letter by Profs. Hughes ...

DR. A. G. EVANS has recently discussed those bimolecular and unimolecular substitutions in which a nucleophilic reagent displaces halogen as halide ion from an alkyl halide 1.

In organic synthesis, replacing lithium with sodium would be a significant achievement because it is >1000 times more ...