Membrane receptors regulate numerous intracellular functions. However, the molecular underpinnings remain poorly understood because most receptors initiate multiple signaling pathways through distinct ...
A number of membrane proteins that are present on the cell membrane control external and internal material transportation, cell protection and signal transmission. The diversity of functions of ...
Receptor tyrosine kinases (RTKs) regulate many critical biological processes such as cell growth, differentiation, and survival through the recruitment of intracellular signaling molecules. The ...
Real world experience with standalone immunotherapy regimens: Immune-related adverse events, healthcare utilization and cost among patients with commercial or Medicare Advantage insurance. This is an ...
A collaborative study on a plant intracellular immune receptor not only shows how an important resistance protein is activated during pathogen infection but also reveals some common operational ...
Research teams explore the activation of plant immune receptors by pathogens. In a recent study, Alexander von Humboldt Professor Jijie Chai at the University of Cologne and his team together with ...
In therapeutic antibody development the fragment crystallizable (Fc) region is far more than just an antigen-binding aid; it's role is much larger, functioning as the antibody’s functional control ...
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How immune signals activate brain circuits to drive sickness-induced social withdrawal
MIT researchers have discovered how an immune system molecule triggers neurons in a specific brain circuit to shut down social behavior in mice modeling infection. "I just can't make it tonight. You ...
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