At the heart of molecular biology is the study of genetic material – DNA and RNA – which serve as the fundamental blueprints for life. These nucleic acids are not only essential for understanding how ...

Figure 1: Crystal structure of the FnCpf1–R-loop complex. Figure 2: PAM recognition and uncoupling of the Watson–Crick dG−1/dC+1 pair. The RNA nuclease site in the WED-III subdomain is located at the ...

Figure 1: Single-particle cryo-EM structure of yeast Pol I elongation complex at 3.8 Å resolution. Available data thus suggest that RNA polymerases can adopt partially expanded and contracted ...

Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are perhaps the most important molecules in cell biology, responsible for the storage and reading of genetic information that underpins all life.