Ageing was long thought to be inevitable, but treatment to forestall it is increasingly argued to be feasible. Of particular interest for such treatments are the ‘senescent’ cells that accumulate with ...

Aged and frail people often suffer a decline in tissue reserve capacity during aging. This reserve, called resilience, helps ...

Senescent “zombie” cells are linked to aging and multiple diseases, but spotting them in living tissue has been notoriously difficult. Researchers at Mayo Clinic have now taken an inventive leap by ...

Not all senescent cells are harmful “zombies” that should be wiped out to prevent age-related disease, according to new research from UC San Francisco, which found that some of them are embedded in ...

Cells that permanently stop dividing have long been recognized as one of the body's defenses against cancer. Now they are also seen as a sometime culprit in cancer and a cause of aging In 1999 Jan M.

Tumor suppressing senescent cells are bad for aging. The no-longer-dividing cells release a continual cascade of inflammatory factors and are implicated in many maladies including arthritis, ...

The quest for rejuvenation treatments often targets senescent cells, despite them having a positive physiological role in health in many recent cases, a leading researcher has warned. In a paper ...

In vivo studies headed by researchers at the Hospital for Sick Children (SickKids), Toronto, have demonstrated that destroying senescent cells in the aging stem cell niche enhances hippocampal ...

Scientists Reappraise the Role of “Zombie” Cells that Anti-Aging Medicine Has Sought to Eliminate Not all senescent cells are harmful “zombies” that should be wiped out to prevent age-related disease, ...

Flawed cells may enter senescence, or cell cycle arrest, to avoid passing on their flaws, but they can still cause trouble. Accumulating year by year and staying metabolically active while secreting ...