New genome sequencing algorithm boosts human genome completeness by 20%, improving variant detection and advancing personalized medicine.

Haoyu Cheng, Ph.D., assistant professor of biomedical informatics and data science at Yale School of Medicine, has developed a new algorithm capable of building complete human genomes using standard ...

Long-read sequencing technologies analyse long, continuous stretches of DNA. These methods have the potential to improve researchers’ ability to detect complex genetic alterations in cancer genomes.

Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) have developed a new machine learning method called SAVANA that significantly reduces sequencing errors for cancer genomes. Long-read ...

Bioinformatics researchers who perform alignments of long protein sequences face a difficult choice: They can get accurate results in hours (sometimes days), or quick results if they're willing to ...