Sphingolipids are found in abundance at synapses and have been implicated in regulation of synapse structure, function, and degeneration. Their precise role in these processes, however, remains ...

Introduction: Alzheimer’s disease (AD) is associated with disturbed metabolism, prompting investigations into specific metabolic pathways that may contribute to its pathogenesis and pathology.

Atherosclerosis—a systemic inflammatory disease—is the number one cause of mortality and morbidity worldwide. As such, the prevention of disease progression is of global interest in order to reduce ...

Phospholipids and sphingolipids are biologically active lipids often referred to as polar lipids that play an important role in maintaining membrane integrity and function. They also play a ...

Asthma is currently defined by reversible airflow obstruction, airway hyperreactivity, and airway inflammation. Of the three diagnostic criteria, asthma symptoms track most closely with airway ...