Nibbler (Nbr) is a 3′-to-5′ exoribonuclease whose catalytic 3′-end trimming activity impacts microRNA (miRNA) and PIWI-interacting RNA (piRNA) biogenesis. Here, we report on structural and functional ...

The functions of biomolecules, including lipids, nucleic acids and especially proteins are determined to a great extent by their structure. This structure–function relationship is a foundation of many ...

American professors Victor Ambros and Gary Ruvkun were honored Monday for their discovery of microRNA, tiny pieces of genetic material that alter how genes work at the cellular level and could lead to ...

STOCKHOLM — Two scientists won the Nobel Prize in physiology or medicine on Monday for their discovery of microRNA, tiny bits of genetic material that serve as on and off switches inside cells that ...

The prize was awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA, which helps determine how cells develop and function. By Teddy Rosenbluth and Derrick Bryson Taylor Victor ...

Abnormal expression and function of microRNA-203 have been linked to various autoimmune diseases, including rheumatoid arthritis and psoriasis. In a new study, researchers investigated microRNA-203 as ...

Proteoglycans are ubiquitous molecules that function as critical components of the extracellular matrix. These proteins are composed of glycosaminoglycan chains that are covalently attached to a ...

STOCKHOLM (AP) — Two Massachusetts scientists won the Nobel Prize in physiology or medicine on Monday for their discovery of microRNA, tiny bits of genetic material that serve as on and off switches ...