Nibbler (Nbr) is a 3′-to-5′ exoribonuclease whose catalytic 3′-end trimming activity impacts microRNA (miRNA) and PIWI-interacting RNA (piRNA) biogenesis. Here, we report on structural and functional ...
The prize was awarded to Victor Ambros and Gary Ruvkun for their discovery of microRNA, which helps determine how cells develop and function. By Teddy Rosenbluth and Derrick Bryson Taylor Victor ...