The randomized ISAT demonstrated the superiority of endovascular treatment in patients with ruptured intracranial aneurysms considered suitable for either clipping or coiling. A later publication ...

Phase II trial designs that ignore between-patient heterogeneity and do not allow for treatment-subgroup interactions may produce very large false positive and false ...

2 Center for Clinical Epidemiology and Evidence-Based Medicine, West China Hospital, Sichuan University, Chengdu, China 3 Basel Institute for Clinical Epidemiology and Biostatistics, University ...

Copyright: © 2005 Elsevier Ltd. Published by Elsevier Ltd. Subgroup analyses can pose serious multiplicity concerns. By testing enough subgroups, a false-positive ...

1 Department of Neurology, Loyola University Medical Center, Maywood, CA, United States 2 Department of Pharmacy, Loyola University Medical Center, Maywood, CA, United States The use of high-dose ...

2 Center for Clinical Epidemiology and Evidence-Based Medicine, West China Hospital, Sichuan University, Chengdu, China 3 Basel Institute for Clinical Epidemiology and Biostatistics, University ...

The extended subgroup ballot functions sub_group_ballot_bit_count, sub_group_ballot_find_lsb, and sub_group_ballot_find_msb are currently written to only consider bits in the ballot corresponding to ...

This example illustrates how to compute and display control limits for the maximum of a subgroup sample. Subgroup samples of 20 metal braces are collected daily, and the lengths of the braces are ...

A brewery monitors its bottling process to ensure that each bottle is filled with the proper amount of beer. The following data set contains the amount of beer recorded in fluid ounces for 23 batches: ...