Deoxyuridine triphosphate (dUTP) metabolism is a critical cellular process that ensures DNA integrity by carefully regulating the balance of nucleotide pools and preventing the incorporation of uracil ...

The DNA packed inside every human cell contains instructions for life, written in billions of letters of genetic code. Every time a cell divides, the complete code, divided among 46 chromosomes, must ...

Researchers have discovered how a metabolite involved in repairing damaged DNA not only controls a person’s sensitivity to cancer therapies but can also protect healthy tissues from damage. The ...