Cyclophosphamide, Thalidomide, and Dexamethasone as Initial Therapy for Patients With Newly Diagnosed Multiple Myeloma in a Middle-Income Country: 7-Year Follow-Up A total of 962 cases of CML on ...

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...

A new study headed by teams at the Wellcome Sanger Institute, EMBL’s European Bioinformatics Institute (EMBL-EBI), and Open Targets has indicated how mutations that cause cancer drug resistance fall ...

Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects ...

A new study reveals 42 hereditary genes which predispose individuals to a higher number of mutations that correlate with a greater probability of developing cancer. A study of 11,000 cancer patients ...

For years scientists have tried to find a gene for conditions like schizophrenia, Alzheimer’s and autism. But the real source could lie in a much more complex genetic puzzle. When Mike McConnell ...

Dose Intensification in Hormone Receptor–Negative and/or Human Epidermal Growth Factor Receptor 2–Negative High-Risk Primary Breast Cancer Authors retain all rights in any data supplements associated ...