Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

A case study reviews the reformulation and scale up of high drug load prototype using wet granulation process for a model formulation. The reformulation of a 100-mg tablet into a 300-mgtablet ...

The authors explain a process for moisture-activated dry granulation in detail and provide guidance for the selection of excipients and equipment. In the pharmaceutical industry, the three most common ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Control of powder properties is crucial for industrial processes across the food, ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Pharmaceutical research and development (R&D) and industry require a continuous fluid-bed dryer that provides a lengthy process time and delivers a high standard for a long time. This article ...