Researchers have discovered that a chemical modification to the synthetic messenger RNA used in therapeutics can cause the cell’s machinery to misread its instructions and result in unintended immune ...

TriLink BioTechnologies senior scientist Dr Cody Palumbo discusses the blockers to manufacturing mRNA-based gene editing ...

RNA molecules can be modified by enzymes through the addition or removal of chemical groups, but the roles of these modifications in the regulation of both mRNAs and non-coding RNAs are not fully ...

Hyperthermophilic archaea are true survival experts. They thrive in boiling hot springs and deep-sea vents—environments ...

In recent years, there has been a rapid increase in the discovery of bacterial immune systems: groups of genes that enable bacteria to protect themselves against viruses known as bacteriophages 1.

Duke researchers published a breakthrough in understanding m6A through the development of a genetically encoded sensor for the most abundant internal mRNA modification. These mRNA modifications are ...

Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of ...